By Icon Health Publications

It is a 3-in-1 reference booklet. It provides an entire scientific dictionary overlaying 1000's of phrases and expressions on the subject of cleft palate. It additionally provides wide lists of bibliographic citations. ultimately, it presents details to clients on the way to replace their wisdom utilizing a number of web assets. The e-book is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to familiarize yourself with examine devoted to cleft palate. in the event that your time is efficacious, this booklet is for you. First, you won't waste time looking the net whereas lacking loads of suitable details. moment, the e-book additionally saves you time indexing and defining entries. eventually, you won't waste time and cash printing thousands of web content.

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Additional info for Cleft Palate - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

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There is considerable evidence that the adhesion of neural crest cells to the extracellular matrix (ECM) is mediated by the integrin family of receptors; however the mechanism by which these cells modulate their integrinmediated adhesion in order to migrate through changing environments is unknown. Recently, we have demonstrated that avian neural crest cells can adapt to and migrate efficiently on a wide range of ECM concentrations in vitro. Interestingly, the extent of adaptation varies along the anterior/posterior (A/P) axis suggesting that differences in integrin regulation may contribute to differences in neural crest migration that thereafter act to restrict developmental potential.

These two common human congenital defects are considered to be multi-factorial traits, having both a significant genetic and environmental component to their etiology. Given the complex pathophysiology of palatal and neural tube closure, the objective of the proposed research program is to utilize recently developed knock out mouse models lacking either a functional folate binding protein receptor (FBP-1) or a functional Ah receptor with which to test critical hypotheses concerning the role of susceptible genotypes on the development of environmentally-induced congenital malformations.

Clearly, this research is of importance to human health, as determining the mechanisms involved will improve the understanding of this disorder leading to a prevention or cure. This research will be conducted under the guidance of Drs. Steven Holladay and Ansar Ahmed of the Virginia-Maryland Regional College of Veterinary Medicine at the VPISU, and will offer excellent training and career development for Dr. Hrubec. ; Dental Ecology; University of North Carolina Chapel Hill Office of Sponsored Research Chapel Hill, Nc 27599 Timing: Fiscal Year 2002; Project Start 01-JAN-1998; Project End 31-DEC-2003 Summary: The purpose of this project is to promote improvement in craniofacial health care outcomes.

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