By Robert Lubow, Ina Weiner

Latent inhibition is a phenomenon wherein publicity to an beside the point stimulus impedes the purchase or expression of conditioned institutions with that stimulus. Latent inhibition, a vital part of the educational procedure, is saw in lots of species. This finished choice of stories of latent inhibition, from various disciplines together with behavioural/cognitive psychology, neuroscience and genetics, specializes in irregular latent inhibition results in schizophrenic sufferers and schizotypal normals. among different issues, the ebook addresses questions comparable to, is latent inhibition an acquisition or functionality deficit? what's the dating of latent inhibition to habituation, extinction, and discovered irrelevance? Does diminished latent inhibition expect creativity? What are the neural substrates, pharmacology, and genetics of latent inhibition? What do latent inhibition learn and theories let us know approximately schizophrenia? This e-book presents a unmarried aspect of reference for neuroscience researchers, graduate scholars, and pros, resembling psychologists and psychiatrists.

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Additional resources for Latent Inhibition: Cognition, Neuroscience and Applications to Schizophrenia

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We focus here on the signature phenomena characteristic of extinction and latent inhibition and on the role accorded “context” in retrieval of the contrasting memories produced by stimulus exposure and conditioning. The second question concerns the conditions that produce the learning that underlies each of these effects. We focus on the role of prediction error, the discrepancy between the actual and predicted outcome of a stimulus presentation, a process that has been invoked to explain a range of acquisition phenomena in Pavlovian conditioning.

Scott, D. S. (1978). Disruption of latent inhibition following systemic administration of parachlorophenylanine (PCPA). Physiology and Behavior, 20, 265–271. Solomon, P. , & Moore, J. W. (1975). Latent inhibition and stimulus generalization of classically conditioned nictitating membrane response in rabbits (Oryctolagus cuniculus) following dorsal hippocampal ablation. Journal of Comparative and Physiological Psychology, 89, 1192–1203. Solomon, P. , & Staton, D. M. (1982). Differential effects of microinjections of d-amphetamine into the nucleus accumbens or the caudate putamen on the rat’s ability to ignore an irrelevant stimulus.

We have also proposed that these contents are closely tied to the cues (physical, temporal, and internal, including emotional states) present across the CS-alone or stimulus-alone exposures. Thus, subsequent behavior is determined by the presence or absence of these cues: their presence retrieves the memory formed across exposures whereas their absence allows the CS to excite its US associate. Finally, in line with contemporary models of acquisition, prediction error is held to regulate associative formation across CS and stimulus-alone exposures.

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