By M. Falempin, J. P. Rousseau (auth.), Claude Roman (eds.)

This quantity studies the newest wisdom within the box of gastrointestinal motility in healthiness and ailment. the themes addressed comprise uncomplicated in addition to scientific facts in regards to the motor services of the complete intestine: the reduce oesophageal sphincter and the gastro-oesophageal reflux; the gastric emptying and the function of the pylorus; the motility of the biliary tract and its issues; the cyclic motor job of the intestine and intestinal transit; the colonic and ano-rectal motility. There also are impOltant contributions in body structure and pharmacology with regards to the neurohumoral rules of the intestine, and the functionality of digestive soft muscle. a number of papers discover the character of the linkage among mind and intestine. a hyperlink which has lengthy been deduced by way of clinicians yet no longer, until eventually lately, systematically explored by way of scientists. the person papers, chosen from various submissions, were topic to 'peer-review' through an inter­ nationwide committee such as either cliniCians and simple scientists. accordingly this e-book should still function an up to the moment resource of data for researchers fascinated by easy sciences in addition to for clinicians in gastroenterology, medication and surgical procedure. C. Roman v This quantity is devoted to the reminiscence of 2 pals and associates: Professor Dr J. HELLEMANS Professor Dr H. MONGES Acknowledgments This used to be the ninth of this sequence of symposia held on the other hand in Europe and North the USA, and the 1st to be held in France.

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Extra resources for Gastrointestinal Motility: Proceedings of the 9th International Symposium on Gastrointestinal Motility held in Aix-en-Provence, France, September 12–16, 1983

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Omplexes stripped barium from the smooth-muscle esophageal segment in a normal fashion. The second wave of the multiphasic wave complex was simultaneous at two or more sites in 34%, appeared retrograde in 4% and was antigrade in 62%. Edrophonium (80 ug/kg IV) increased the number and amplitude of the phasic waves, whereas atropine (3 ug/kg IV) reduced the number and amplitude, often to a single-peaked peristaltic complex. Only 2 subjects in the control groups demonstrated multiphasic peristaltic pressure complexes phenomenon.

As cutting both ganglia was usually followed by death of the animals, section of one vagus nerve was associated with division of the contralateral nodose ganglion. Thus oesophageal motility and transit had to be compared in ipsilaterally vagotomized sheep, before and after the section of the contralateral nodose ganglion to assess the role of oesophageal afferents. Evidence of deafferentation of the entire thoracic oesophagus or of its last 10-15 cm has come from the failure of inflated balloons to elicit local reflex contractions or secondary peristalsis during distension of the presumed deafferented part of the oesophagus, in contrast to what was observed in the vagotomized sheep before ganglionectomy.

1). - In contrast no difference was found due to duration of diabetic state or to insulin-dependence. DISCUSSION In DP, decreased velocity of peritalsis, incomplete relaxation of LES, and high frequency of abnormal motor activity of esophagus suggest a dysfunction of the autonomous nervous system. Absence of variation in the amplitude of waves accounts for the integrity of the smooth muscle (5). In our study repetitive and simultaneous waves are significantly more frequent in DP with or without PN than in controls.

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