By Phillip M. Devlin MD

Written by means of the most important specialists within the box, this quantity is a accomplished textual content and useful reference on modern brachytherapy. The ebook presents unique, site-specific info on purposes and strategies of brachytherapy within the head and neck, significant anxious procedure, breast, thorax, gastrointestinal tract, and genitourinary tract, in addition to on gynecologic brachytherapy, low dose fee and excessive dose price sarcoma brachytherapy, vascular brachytherapy, and pediatric applications.

The e-book completely describes and compares the 4 significant options utilized in brachytherapy—intracavity, interstitial, surface-dose or mildew remedy, and transluminal. Chapters element specific innovations which are acceptable in particular medical situations.

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Extra info for Brachytherapy: Applications and Techniques

Example text

The potential for movement of applicator and organ with respiration, and between fractions, and during long LDR hospitalizations must be recognized, planned for, and accounted for. A number of image modalities offer support for the placement, delivery, or evaluation of brachytherapy. X-ray A pair of x-ray films can be used to localize the position of applicators, seeds, or other radiopaque landmarks within the patient. In the event that filming on a simulator within the department is not an option, jigs of known geometry and reference points can be used.

Int J Radiat Oncol Biol Phys. 1990;19:281–286. Fertil B, Malaise EP. Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published cell curves. Int J Radiat Oncol Biol Phys. 1985;11:1699–1707. Petereit DG, Pearcey R. Literature analysis of high dose rate brachytherapy fractionation schedules in the treatment of cervical cancer: Is there an optimal fractionation schedule? Int J Radiat Oncol Biol Phys. 1999;43:359–366. Orton CG, Seyedsadr M, Somnay A.

Ning S, Knox SJ. G2/M-phase arrest and death by apoptosis of HL60 cells irradiated with exponentially decreasing low-dose-rate gamma radiation. Radiat Res. 1999;151:659–669. 35. McKeown SR, Jones B. DNA repair: Therapeutic implications. Br J Radiol. 2006;79:91–93. Chapter 1: Radiobiologic Concepts for Brachytherapy 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 19 Tan LT, Jones B, Green JA, et al. The treatment of carcinomas of the uterine cervix after initial external beam radiotherapy: A pilot study using integrated cytotoxic chemotherapy prior to brachytherapy.

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