By Anthony F. Shields, Pat Price

A number of state-of-the-art imaging strategies, together with their use for top perform, are addressed during this ebook. The ebook additionally offers examples of effects present in either pre-clinical and medical reports. This finished textual content covers the complete spectrum of in vivo imaging for oncology. it is going to aide clinicians in any respect degrees in maintaining with the main state-of-the-art recommendations.

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Adv Pharmacol Chemother 1984;20: 1–20. 29. Zee-Cheng RK, Cheng CC. Screening and evaluation of anticancer agents. Methods Find Exp Clin Pharmacol 1988;10(2):67–101. 30. Jackson RC. The problem of the quiescent cancer cell. Adv Enzyme Regul 1989;29:27–46. 31. DiGiovanni J. Modification of multistage skin carcinogenesis in mice. Prog Exp Tumor Res 1991; 33:192–229. 32. Konishi Y, Tsutsumi M, Tsujiuchi T. Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters. Pancreas 1998;16(3):300–306.

3. Diffusion MRI of Panc-1 subcutaneous xenograft treated with Gemzar (160 mg/kg Q3D × 4 IP). On the left, ADC maps are shown of a single slice on day 46 for control (vehicle) and treated tumors from two different animals. Control tumor ADC values are approximately 75 × 10−5 mm2/sec; the treated tumor has focal regions with ADC values approaching 130 × 10−5 mm2/sec. Tumor burden (mean fold growth) is plotted in the upper right panel, and mode tumor ADC change relative to pretreatment values in the lower right panel.

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