By Yasumasa Nishimura, Ritsuko Komaki

Successful medical use of intensity-modulated radiation treatment (IMRT) represents an important strengthen in radiation oncology. simply because IMRT can carry high-dose radiation to a goal with a discounted dose to the encompassing organs, it may well enhance the neighborhood keep watch over expense and decrease toxicities linked to radiation remedy. considering that IMRT started getting used within the mid-1990s, a wide quantity of medical facts of the benefits of IMRT has been accumulated. even though, therapy making plans and caliber coverage (QA) of IMRT are complex and tough for the clinician and the clinical physicist. This publication, by means of authors well known for his or her services of their fields, offers cumulative medical proof and acceptable strategies for IMRT for the clinician and the physicist. half I bargains with the rules and strategies, background, rules, QA, therapy making plans, radiobiology and similar features of IMRT. half II covers scientific functions with a number of case stories, describing contouring and dose distribution with scientific effects in addition to descriptions of symptoms and a overview of medical facts for every tumor web site. the knowledge offered during this booklet serves as a necessary source for the training clinician and physicist.

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Extra resources for Intensity-Modulated Radiation Therapy: Clinical Evidence and Techniques

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Radiother Oncol 89(2):180–191 32. Das IJ, Moskvin V, Johnstone PA (2009) Analysis of treatment planning time among systems and planners for intensity-modulated radiation therapy. J Am Coll Radiol 6(7):514–517 33. De Gersem W, Claus F, De Wagter C, Van Duyse B, De Neve W (2001) Leaf position optimization for step-and-shoot IMRT. Int J Radiat Oncol Biol Phys 51(5):1371–1388 34. de Greef M, Crezee J, van Eijk JC, Pool R, Bel A (2009) Accelerated ray tracing for radiotherapy dose calculations on a GPU.

82. Moran JM, Dempsey M, Eisbruch A, Fraass BA, Galvin JM, Ibbott GS, Marks LB (2011) Safety considerations for IMRT: executive summary. Med Phys 38(9):5067–5072 83. Murphy MJ (2012) Kilovoltage radiography for robotic linac IGRT. In: Bourland JD (ed) Image-guided radiation therapy, Imaging in medical diagnosis and therapy. CRC Press, Boca Raton, pp 147–155 84. Mutic S, Low DA, Klein EE, Dempsey JF, Purdy JA (2001) Room shielding for intensitymodulated radiation therapy treatment facilities. Int J Radiat Oncol Biol Phys 50(1):239–246 85.

Smith JC, Dieterich S, Orton CG (2011) It is STILL necessary to validate each individual IMRT treatment plan with dosimetric measurements before delivery. Med Phys 38(2):553–555 112. Solaiappan G, Singaravelu G, Prakasarao A, Rabbani B, Supe SS (2009) Influence of photon beam energy on IMRT plan quality for radiotherapy of prostate cancer. Rep Pract Oncol Radiother 14(1):18–31 113. Stein J, Bortfeld T, Dorschel B, Schlegel W (1994) Dynamic X-ray compensation for conformal radiotherapy by means of multi-leaf collimation.

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