By Peter J. H. Scott

This booklet describes equipment and methods for getting ready puppy radiopharmaceuticals, and highlights new equipment for carrying out radiochemical reactions with carbon-11 (C11) and fluorine-18 (F18), that are of the main prevalent radionuclides in positron emission tomography (PET) imaging.

•    Provides trustworthy equipment for radiochemical syntheses and reactions, together with all crucial info to copy the procedure
•    Eliminates the time-consuming technique of looking out magazine articles and extracting pertinent information from long experimental sections or aiding information
•    Focuses on an rising and demanding zone for pharmaceutical and clinical applications
•    Encompasses technical, regulatory, and alertness aspects
•    Includes solid-phase radiochemistry, transition-metal catalyzed radiochemistry, microfluidics, click on chemistry, eco-friendly radiochemistry and new techniques for radiopharmaceutical quality controls

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Additional resources for Radiochemical Syntheses, Volume 2: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production

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H. Scott and B. G. Hockley, editors, John Wiley and Sons, Hoboken, NJ, 2012. 8. M. Nader, A. Hoepping, Nuklearmedizin, 2005, 44 (A192), 7. 9. A. Sperandeo, A. Cistaro, N. Paligoric, D. Busetta, R. Mangiapane, U. Ficola, J Nucl Med, 2009, 50 (Suppl. 2), 28. 10. X. Shao, B. G. Hockley, R. Hoareau, P. L. Schnau, P. J. H. Scott, Appl Rad Isotop 2011, 69, 403. 11. M. E. Rodnick, A. F. Brooks, B. G. Hockley, B. D. Henderson, P. J. H. Scott, Appl Rad Isotop, 2013, 78, 26. 12. Virgin [18O]H2O purchased from ABX or Rotem and used as received.

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2009. 24. , United States (part no. 9578‐3). 25. , United States. 26. Shimadzu Corporation, United States. 27. , United States. Unlabeled reference standard was purchased from ABX advanced biochemicals (part no. 6130). 29. B. H. Mock, W. Winkle, M. T. Vavrek, Nucl Med Biol, 1997, 24, 193. 30. Charles River Laboratories, USA. US Pharmacopeia <85>. Bacterial endotoxins test. US Patent 32–NF 27. 2009. 32. Becton, Dickinson and Company, USA. US Pharmacopeia <71>. Sterility tests. US Patent 32–NF 27.

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