By J.L. Meyer, B.D. Kavanagh, J.A. Purdy, R. Timmerman, W. Hinkelbein
Over the past four years, "IMRT, IGRT, SBRT: Advances within the therapy making plans and supply of Radiotherapy" has turn into a customary reference within the box. in this time, despite the fact that, major growth in high-precision applied sciences for the making plans and supply of radiotherapy in melanoma therapy has known as for a moment version to incorporate those new advancements. completely up-to-date and prolonged, this re-creation bargains a complete consultant and review of those new applied sciences and the numerous scientific remedy courses that convey them into functional use. Advances in intensity-modulated radiotherapy (IMRT), and 4D and adaptive therapy making plans are truly provided. objective localization and image-guided radiotherapy (IGRT) platforms are comprehensively reviewed to boot. scientific tutorials illustrate aim definitions for the key melanoma websites, and necessary concepts for organ movement administration are defined and in comparison. There also are a number of chapters that discover the technical foundation and most modern scientific event with stereotactic physique radiotherapy (SBRT) and summarize functional therapy ideas. moreover, the numerous and lengthening contributions of proton treatment to melanoma care also are highlighted, along the sensible allocation of most of these new applied sciences from an monetary viewpoint. As a spotlight of this quantity, a few pictures may be seen on-line in time-elapse movies for higher readability and extra dynamic visualization Written via best professionals within the box, this complete quantity brings scientific and technical practitioners of radiotherapy absolutely modern with the most important advancements in gear, applied sciences and remedy guidance.
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Additional info for IMRT, IGRT, SBRT: Advances in the Treatment Planning and Delivery of Radiotherapy (Frontiers of Radiation Therapy and Oncology)
Example text
Int J Radiat Oncol Biol Phys 2001; 51: 880–914. 47 Vijayakumar S, Narayan S, Yang C, et al: Use of benchmark dose-volume histograms in radiotherapy treatment planning for prostate cancer; in Meyer JL (ed): Advances in the Treatment Planning and Delivery of Radiotherapy. Front Radiat Ther Oncol. Basel, Karger, 2006, vol 40, pp 180–192. 48 Purdy JA: Future directions in 3-D treatment planning and delivery: a physicist’s perspective. Int J Radiat Oncol Biol Phys 2000; 46:3–6. Prof. James A. Purdy, PhD Department of Radiation Oncology, UC Davis Medical Center 4501 X Street, Suite G140 Sacramento, CA 95816 (USA) Tel.
These models utilize convolution energy deposition kernels that describe the distribution of dose about a single primary photon interaction site, and provide accurate results even for complex heterogeneous geometries. It is the author’s opinion that heterogeneity-corrected treatment plans generated using such advanced algorithms should be the standard of practice for IGRT. The study by Frank et al. [25] provides a clear methodology for safely transitioning clinical use from one based on planning that assumes a homogeneous unit density patient, to one using a heterogeneous patient model.
Furthermore, since IMRT treatments typically take longer than two-dimensional radiotherapy or 3DCRT treatments, the patient must remain in the fixed treatment position for a longer period of time, increasing the susceptibility to intrafraction geometric uncertainties. All of these factors contribute to IMRT being a ‘less forgiving’ form of radiation therapy with regard to the effects of geometric uncertainties, and this imposes more stringent requirements to account for both intrafraction and interfraction uncertainties.
